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J Biol Chem (2007) 282(48):35405–15.10.1074/jbc.M705814200 143 De Rocca Serra-NedelecAEdouardTTreguerKTajanMArakiTDanceMet alNoonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature

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The findings are specific, and one of them is very commonly reported backwards: BPC-157 did not directly increase fibroblast proliferation — MTT assay showed no direct effect It did significantly increase cell survival under hydrogen peroxide oxidative stress It increased fibroblast migration in a dose-dependent manner It induced F-actin formation and dose-dependently increased phosphorylation of FAK and paxillin — proteins central to the cell migration pathway [2] The distinction matters